Projekt S 03/18 "Evidenz- und konsensbasierte Indikationskriterien zur Hüfttotalendoprothese (EKIT-Hüfte)"
2022Lützner C, Deckert S, Günther K-P, Postler AE, Lützner J, Schmitt J, Limb D, Lange T. Indication Criteria for Total Hip Arthroplasty in Patients with Hip Osteoarthritis—Recommendations from a German Consensus Initiative. Medicina 58(5): 574, 2022 April 22.
>> Indikationskriterien für die totale Hüftendoprothetik bei Patienten mit Hüftarthrose – Empfehlungen einer deutschen Konsensusinitiative
2022Lützner C, Postler A, Druschke D, Riedel R, Günther K-P, Lange T. Ask patients what they expect! A survey among patients awaiting total hip arthroplasty in Germany. The Journal of Arthroplasty, 2022 März 25.
>> Fragen Sie die Patienten, was sie erwarten! Eine Umfrage unter Patienten, die in Deutschland auf eine totale Hüftendoprothetik warten
2021 Günther K-P, Deckert S, Lützner C, Lange T, Schmitt J, Postler A "Hüfttotalendoprothese bei Coxarthrose – evidenzbasierte und patientenorientierte Indikationsstellung" Deutsches Ärzteblatt DOI 10.3238/arztebl.m2021.0323
>> Hüfttotalendoprothese bei Coxarthrose - evidenzbasierte und patientenorientierte Indikationsstellung
"Ein klinisch-radiologischer Score für Femurkopftransplantate"
2020 Siemssen N, Friesecke C, Wolff C, Beller G, Wassilew K, Neuner B,
Schoenfeld H,et al 2020 "Ein klinisch-radiologischer Score für
Femurkopftransplantate. Etablierung des Tabea-FK-Scores zur Sicherung
der Qualität humaner Femurkopftransplantate." Orthopäde DOI
10.1007/s00132-020-03941-5
>> Ein klinisch-radiologischer Score für Femurkopftransplantate
Projekt S 03/17 "Einfluss des spino-pelvinen Alignements und der dreidimensionalen patientenindividuellen Rekonstruktion der Hüftgeometrie auf das klinische Outcome nach primärem Hüftgelenksersatz – eine prospektive, EOS-Imaging basierte Studie"
2021 Innmann MM, Merle C, Phan P, Beaulé PE,
Grammatopoulos G. "Differences in Spinopelvic Characteristics Between Hip Osteoarthritis Patients and Controls" The Journal of Arthroplasty 2021
March 18. DOI: https://doi.org/10.1016/j.arth.2021.03.031
>> Differences in Spinopelvic Characteristics Between Hip Osteoarthritis Patients and Controls
2021 Innmann MM, Reichel F, Schaper B, Merle C, Beaulé PE, Grammatopoulos G. "How Does Spinopelvic Mobility and Sagittal Functional Cup Orientation Affect Patient-Reported Outcome 1 Year after THA?—A Prospective Diagnostic Cohort Study" The Journal of Arthroplasty 2021
February 09. DOI:https://doi.org/10.1016/j.arth.2021.02.014
>> How Does Spinopelvic Mobility and Sagittal Functional Cup Orientation Affect Patient-Reported Outcome 1 Year after THA?—A Prospective Diagnostic Cohort Study
2020 Innmann MM, Merle C, Phan P, Beaulé PE, Grammatopoulos G. "How Can Patients With Mobile Hips and Stiff Lumbar Spines Be Identified Prior to Total Hip Arthroplasty? A Prospective, Diagnostic Cohort Study" The Journal of Arthroplasty 2020
Feb 12. DOI: https://doi.org/10.1016/j.arth.2020.02.029
>> Wie können Patienten mit mobilen Hüften und steifen Lumbar-Spines vor der totalen Hüftarthroplastik identifiziert werden? Eine prospektive, diagnostische Kohortenstudie
2019 Innmann, MM, Merle, C, Gotterbarm, T, Ewerbeck, V, Beaulé, PE, Grammatopoulos, G. "Can spinopelvic mobility be predicted in patients awaiting total hip arthroplasty? A prospective, diagnostic study of Patients with end-stage HIP Osteoarthritis" The Bone & Joint Journal 2019. doi:10.1302/0301-620X.101B8.BJJ-2019-0106.R1
>> Can spinopelvic mobility be predicted in patients awaiting total hip arthroplasty? A prospective, diagnostic study of Patients with end-stage HIP Osteoarthritis.
2019 Innmann, M, Merle, C, Gotterbarm, T, Ewerbeck, V, Beaulé, PE, Grammatopoulo, G. "Can spinopelvic mobility be predicted in patients awaiting total hip arthroplasty? A prospective, diagnostic study of patients with end-stage HIP osteoarthritis." DOI: :10.1302/0301-620X.101B8. BJJ-2019-0106.R1.
>> Can spinopelvic mobility be predicted in patients awaiting total hip arthroplasty?
Projekt S 02/17 "Belastbarkeit von Palacos-Zementspacern nach Knieprothesenausbau."
2019 Chong, S., Shen, L. & Frantz, S. Loading capacity of dynamic knee spacers: a comparison between hand-moulded and COPAL spacers. BMC Musculoskelet Disord 20, 613 (2019) DOI:10.1186/s12891-019-2982-5
>> Loading capacity of dynamic knee spacers: a comparison between hand-moulded and COPAL spacers
Projekt S 01/17 "Wirkung von Lavanox auf humane Zellen und Bakterien"
2020 Röhner E, Jacob B, Böhle S, Rohe S, Löffler B, Matziolis G, Zippelius T, " Sodium jypochlorite ist more effectibve than chlorhexidine for eradication of bacterial biofilm of staphylodcocci and Pseudomonas aeruginosa. Knee Surg Sports Traumatol Arthrosc. 2020 Feb 7. doi: 10.1007/s00167-020-05887-9
>> Sodium hypochlorite is more effective than chlorhexidine for eradication of bacterial biofilm of staphylococci and Pseudomonas aeruginosa.
Projekt S 01/16 "Regulation von TGF-beta"
2018 Drynda S, Drynda A, Feuerstein B, Kekow J, Lohmann CH, Bertrand J. "The effects of cobalt and chromium ions on transforming growth factor-beta patterns and mineralization in human osteoblast-like MG63 and SaOs-2 cells." DOI: 10.1002/jbm.a.36409.
>> The effects of cobalt and chromium ions on transforming growth factor‐beta patterns and mineralization in human osteoblast‐like MG63 and SaOs‐2 cells
2018 Drynda S, Drynda A, Kekow J, Lohmann CH, Bertrand J. "Differential Effect of Cobalt and Chromium Ions as Well as CoCr Particles on the Expression of Osteogenic Markers and Osteoblast Function." DOI: 10.3390/ijms19103034.
>> Differential Effect of Cobalt and Chromium Ions as Well as CoCr Particles on the Expression of Osteogenic Markers and Osteoblast Function.
Projekt S 01/15 "Veränderungen der kognitiven Leistungsfähigkeit älterer Menschen durch die Implantation einer Hüfttotalendoprothese"
2022 Strahl A, Kazim MA, Kattwinkel N, Hauskeller W, Moritz S, Arlt S, Niemeier A."Mid-term improvement of cognitive performance after total hip arthroplasty in patients with osteoarthritis of the hip: A prospective cohort study." Bone Joint J. 2022 Mar;104-
B(3):331-340. DOI: 10.1302/0301-620X.104B3.BJJ-2020-2021.R2. PMID: 35227089.
>>Mid-term improvement of cognitive performance after total hip arthroplasty in patients with osteoarthritis of the hip: A prospective cohort study
2022 Kazim MA, Strahl A, Moritz S, Arlt S, Niemeier A. Chronic pain in osteoarthritis of the hip is associated with selective cognitive impairment. Arch Orthop Trauma Surg. 2022 May 5. DOI: 10.1007/s00402-022-04445-x. Epub ahead of print. PMID: 35511355.
>> Chronische Schmerzen bei Osteoarthritis der Hüfte sind mit selektiven kognitiven Beeinträchtigungen verbunden
Projekt S 01/14 "Kleinkopf Metall-Metall-Gleitpaarung."
2020 Tobias Reiner, Matthias C. Klotz, Kirsten Seelmann, Fabian Hertzsch, Moritz M. Innmann, Marcus R. Streit, Timo A. Nees, Babak Moradi, Christian Merle, Jan Philippe Kretzer and Tobias Gotterbarm "Long-Term Results of a Second-Generation, Small-Diameter, Metal-On-Metal Bearing in Primary Total Hip Arthroplasty at 14-Year Follow-Up." Materials 2020, 13, 557; doi:10.3390/ma13030557
>> Long-Term Results of a Second-Generation, Small-Diameter, Metal-On-Metal Bearing in Primary Total Hip Arthroplasty at 14-Year Follow-Up
2017 Reiner, T., Do, T., Klot, M., Hertzsch, F., Seelmann, K., Gaida, M., Weber, M.A., Gotterbarm, T. "MRI Findings in Patients After Small-Head Metal-on-Metal Total Hip Arthroplasty with a Minimum Follow-up of 10 Years." The Journal of Bone and Joint Surgery-American Volume. 99A(18):1540–1546, SEPTEMBER 20, 2017 DOI: 10.2106/JBJS.16.01021
>> MRI Findings in Patients After Small-Head Metal-on-Metal Total Hip Arthroplasty with a Minimum Follow-up of 10 Years
Projekt S 02/14 "Belastungsanalyse Glenoidkomponenten"
2018 Sowa B, Bochenek M, Braun S, Zeifang F, Kretzer JP, Bruckner T, Walch G, Raiss P. "Replacement options for the B2 glenoid in osteoarthritis of the shoulder: a biomechanical study." Arch Orthop Trauma Surg. DOI 10.1007/s00402-018-2915-z.
>> Replacement options for the B2 glenoid in osteoarthritis of the shoulder: a biomechanical study.
2018 Sowa B, Bochenek M, Braun S, Kretzer JP, Zeifang F, Bruckner T, Walch G, Raiss P., "The subchondral bone layer and glenoid implant design are relevant for primary stability in glenoid arthroplasty." Arch Orthop Trauma Surg. DOI 10.1007/s00402-018-2990-1.
>> The subchondral bone layer and glenoid implant design are relevant for primary stability in glenoid arthroplasty.
Projekt S 01/13 "EPRD"
2015 Jan Sternkopf "Acceptance of Process Innovations in Hospitals: Insights from the German Arthroplasty Register" DOI 10.1007/978-3-319-12178-9_7.
>> Acceptance of Process Innovations in Hospitals: Insights from the German Arthroplasty Register
2014 Jan Sternkopf, Thoralf R. Liebs, Carsten Schultz "Endoprothesenregister - Große Akzeptanz in Krankenhäusern" Deutsches Ärzteblatt, Jg. 111, Heft 43, 24.10.2014.
>> Endoprothesenregister - Große Akzeptanz in Krankenhäusern
Projekt S 01/11 "Glenoid Component Loosening"
2014 Patrick Raiss, MD, Thomas Bruckner, PhD, Markus Rickert, MD, and Gilles Walch, MD "Longitudinal Observational Study of Total Shoulder Replacements with Cement" J Bone Joint Surg Am. 2014;96:198-205 dx.doi.org/10.2106/JBJS.M.00079
>> Longitudinal Observational Study of Total Shoulder Replacements with Cement
Projekt S 05/10"Abriebreaktionen"
2012 Heiko Meyer MD, Tina Mueller BS, Gesine Goldau BS, Kathrin Chamaon PhD, Marcel Ruetschi MD, Christoph H. Lohmann MD „Corrosion at the Cone/Taper Interface Leads to Failure of Large-diameter Metal-on-Metal Total Hip Arthroplasties“ Clin. Orth. Rel. Res. DOI 10.1007/s11999-012-2502-5
>>Corrosion at the Cone/Taper Interface Leads to Failure of Large-diameter Metal-on-metal Total Hip Arthroplasties
Projekt S 02/10 „3-D- Analysis“
2013 Christian Merle, Wenzel Waldstein, Jennifer S. Gregory, Simon R. Goodyear, Richard M. Aspden, Peter R. Aldinger, David W. Murray, Harinderjit S. Gill „Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis“ Hip Int 2013; 23 (5); 484-491 DOI: 10.5301/hipint.5000040
>>Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis
2013 Christian Merle, MD, MSc, George Grammatopoulos, MD, Wenzel Waldstein, MD, Elise Pegg, PhD, Hemant Pandit, MBBS (Bombay), MS (Orth), DNB (Orth), FRCS (Orth), DPhil, Peter R. Aldinger, MD, PhD, Harinderjit S. Gill, BEng, DPhil, and David W. Murray, MA, MD, FRCS (Orth) „Comparison of Native Anatomy with Recommended Safe Component Orientation in Total Hip Arthroplasty for Primary Osteoarthritis“ The Journal of Joint and Bone Surgery, 2013; 95:e172(1-7), DOI.org/10.2106/JBJS.L.01014
>>Comparison of Native Anatomy with Recommended Safe Component Orientation in Total Hip Arthroplasty for Primary Osteoarthritis
2013 C. Merle, W. Waldstein, J. S. Gregory, S. R. Goodyear, R. M. Aspden, P. R. Aldinger, D. W. Murray, H. S. Gill „How Many Different Types of Femora are There in Primary Hip Osteoarthritis? An Active Shape Modeling Study“ Journal of Orthopaedic Research,Online Library Wiley DOI/10.1002/jor.22518/
>>How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study
2012 C. Merle, W. Waldstein, E. Pegg, M. R. Streit, T. Gotterbarm, P. R. Aldinger, D. W. Murray, H. S. Gill "Femoral offset is underestimated on anteroposterior radiographs of the pelvis but accurately assessed on anteroposterior radiographs of the hip" The Journal of Joint and Bone Surgery, Vol. 94-B No. 4, 04. April 2012
>>Femoral offset is underestimated on anteroposterior radiographs of the pelvis but accurately assessed on anteroposterior radiographs of the hip
2012 C. Merle, W. Waldstein, E. C. Pegg, M. R. Streit, T. Gotterbarm, P. R. Aldinger, D. W. Murray, H. S. Gill "Prediction of three-dimensional femoral offset from AP pelvis radiographs in primary hip osteoarthritis" European Journal of Radiology, DX.DOI.org/10.1016/j.ejrad.2013.02.040
>>Prediction of three-dimensional femoral offset from AP pelvis radiographs in primary hip osteoarthritis
Projekt S 04/09 „T-Zell-Populationen"
2013 Peter Thomas, Christine von der Helm, Christoph Schopf, Marc Thomsen, Lars Frommelt, Josef Schneider, Michael Flaig, Veit Krenn, Farhad Mazoochian, Burkhard Summer „Periimplant Histology and Cytokine Pattern in Metal-Allercic Knee Arthroplasty Patients with Improvement After Revision with Hypoallergenic Materials“ Elsevier Seminars in Arthroplasty, Dec. 2012, Vol. 3, Issue 4, pp. 268-272
Projekt S 02/09 „Psychische Prädiktoren"2013 Michael T. Hirschmann, Enrique Testa, Felix Amsler, Niklaus F. Friederich „The unhappy total knee arthroplasty (TKA) patient: higher WOMAC and lower KSS in depressed patients prior and after TKA“ Knee Surg Sports Tramatol Arthrose DOI 10.1007/s00167-013-2409-z 01/2013
>>The unhappy total knee arthroplasty (TKA) patient: higher WOMAC and lower KSS in depressed patients prior and after TKA
Projekt S 03/08 "Knie-TEP"2012 Pfitzner T, Röhner E, Krenn V, Perka C, Matziolis G. „BMP-2 Dependent Increase of Soft Tissue Density in Arthrofibrotic TKA" Open Orthop J. 2012;6:199-203. doi: 10.2174/ 1874325001206010199. Epub 2012 May 16
>>BMP-2 Dependent Increase of Soft Tissue Density in Arthrofibrotic TKA
2012 Pfitzner T, Geissler S, Duda G, Perka C, Matziolis G. “Increased BMP expression in arthrofibrosis after TKA" Knee Surg Sports Traumatol Arthrosc. 2012 Sep;20(9):1803-8. doi: 10.1007/s00167-011-1774-8. Epub 2011 Nov 17
>>Increased BMP expression in arthrofibrosis after TKA
Projekt S 02/08 „Scaffolds“
2009 Pawel Skadlubowicz, Zdzislaw Krol, Zygmunt Wrobel, Fritz Hefti, Andreas Krieg „Using of statistical shape models for pelvis reconstruction in the oncologic surgery“ Journal of Medical Informa-tics and Techno-logies, Vol. 13, Oct. 2009, pp. 151-156
>>Using of statistical shape models for pelvis reconstruction in the oncologic surgery
2011 Beat Göpfert, Zdzislaw Krol, Marie Freslier, Andreas Krieg „3D video-based deformation measurement of the pelvis bone under dynamic cyclic loading“ Biomed Eng Online. 0: 60. July 17, 2011; doi 10.1186/1475-925X-10-60
>>3D video-based deformation measurement of the pelvis bone under dynamic cyclic loading
Projekt S 01/08 „Serum Particles“
2011 Samira Daou, Antoun El Chemaly, Panayotis Christofilopoulos, Louis Bernard, Pierre Hoffmeyer, Nicolas Demaurex „The potential role of cobalt ions released from metal prosthesis on the inhibition of Hv1 proton channels and the decrease in Staphylococcus epidermidis killing by human neutrophils“ Elsevier, J. of Biomaterials 32 (2011) pp. 1769 – 1777
>>The potential role of cobalt ions released from metal prosthesis on the inhibition of Hv1 proton channels and the decrease in Staphyloccocus epidermidis killing by human neutrophils
Projekt S 02/07 „Schulter“
2011 Raewyn C. Poulsen, Andrew J. Carr, Philippa A. Hulley „Protection against glucocorticoid-induced damage in human tennocytes by modulation of ERK, Akt and Forkhead signaling“ Endocrinology Feb. 2011 152(2):503-514
>>Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling
Projekt S 01/07 „Trabekel“
2007 Busse, B; Niecke, M; Püschel, K; Delling, G: Katzer, A; Hahn, M. „Polyethylen-Abrieb: Ursache oder Folge einer Endoprothesenlockerung? Untersuchungen an festen und gelockerten Hüftendoprothesen“ Zeitschrift für Orthopädie und Unfallchirurgie
>>Polyethylen-Abrieb: Ursache oder Folge einer Endoprothesenlockerung? Untersuchungen an festen und gelockerten Hüftendoprothesen
2008 Busse, B.; Hahn, M.; Niecke, M.; Jobke, B.; Püschel, K.; Delling, G.; Katzer, A. „Allocation of nonbirefringent wear debris: Darkfield illumination associated with PIXE microanalysis reveals cobalt deposition in mineralized bone matrix adjacent to CoCr implants“ Journal of Biomedical Materials Research Part A,Vol. 87A Issue 2, pages 536-545
>>Allocation of nonbirefringent wear debris: darkfield illumination associated with PIXE microanalysis reveals cobalt deposition in mineralized bone matrix adjacent to CoCr implants.
2009 Busse, B.; Hahn, M.; Soltau, M.; Zustin, J.; Püschel, K.; Duda, G.; Amling, M. „Increased calcium content and inhomogeneity of mineralization render bone toughness in osteoporosis“ Elsevier Bone 45 Dez. 2009 pp. 1034-1043
>>Increased calcium content and inhomogeneity of mineralization render bone toughness in osteoporosis: mineralization, morphology and biomechanics of human single trabeculae
2010 Busse, B.; Hahn, M.; Schinke, Th.; Püschel, K.; Duda, G.; Amling, M. „Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling“ Journal of Biomedical Materials Research Part A, Vol. 92 A Issue 4, 1440-1451
>>Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling.
2010 Busse, B.; Jobke, B; Hahn, M.; Priemel, M.; Niecke, M., Seitz, S.; Zustin, J.; Semler, J.; Amling, M. „Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in meralization and microstructure“ Acta Biomaterialia 2010.07.019
>>Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in mineralization and microstructure.
Projekt S 05/06 „PMMA“
2009 Elter P, Thull R. „Freisetzung von Antibiotikamischungen aus Polymethylmethacrylat-Knochenzement „Zeitschr. BIOma-terialien 2009: 10 (1/2): S. 18 – 24
Projekt S 04/06 „Genexpression“
2008 Morawietz L, Weimann A, Schroeder JH, Kuban RJ, Ungethuem U, Kaps C, Slevogt H, Gehrke T, Krukemeyer MG, Krenn V. „Gene expression in endoprosthesis loosening: chitinase activity for early diagnosis?“ J Orthop Res. 2008 Mar;26(3)
>>Gene expression in endoprosthesis loosening: chitinase activity for early diagnosis?
2008 Lars Morawietz, Frank Schaeper, Joerg H. Schroeder, Tserenchunt Gansukh, Nachin Baasanjav, Manfred G. Krukemeyer, Thorsten Gehrke und Veit Krenn „Computer-assisted validation of the synovitis score“ Virchows Archiv, Volume 452, Number 6 / Juni 2008
>>Computer-assisted validation of the synovitis score.
2008 L. Morawietz , G. Fernahl und V. Krenn „Differenzialdiagnostik der Synovialitis“ Der Pathologe, Vol. 29, Suppl. 2, Nov. 2008
>>Differenzialdiagnostik der Synovialitis
2009 Lars Morawietz, Obbe Tiddens, Michael Mueller, Stephan Tohtz, Tserenchunt Gansukh, Joerg H Schroeder,1 Carsten Perka1 & Veit Krenn „Twenty-three neutrophil granulocytes in 10 high-power fields is the best histopathological threshold to differentiate between aseptic and septic endoprosthesis loosening“ Histopathology 2009, 54, 847–853
>>Twenty‐three neutrophil granulocytes in 10 high‐power fields is the best histopathological threshold to differentiate between aseptic and septic endoprosthesis loosening
Projekt S 04/05 „Knorpel“
2009 H.Voigt, A. Lemke, R. Mentlein, M. Schünke, B. Kurz „Tumor necrosis factor alpha-dependent aggrecan clevage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro“ Arthritis Research & Therapy 2009, 11:R141
>>Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro
2010 Lemke AK, Sandy JD, Voigt H, Dreier R, Lee JH, Grodzinsky AJ, Mentlein R, Fay J, Schünke M, Kurz B. (2010) „Interleukin-1alpha treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2“ Cell Tissue Res. (online)
>>Interleukin-1α treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2.
2010 V. Krenn, P. Knöß, W. Rüther, M. Jakobs, M. Otto, M.G. Krukemeyer, A. Heine, G. Möllenhoff, B. Kurz „Meniskusdegenerationsscore und NITEGE-Expression“ Der Orthopäde, (online)
>>Meniskusdegenerationsscore und NITEGE-Expression
2012 M. Hufeland, M. Schünke, A.J. Grodzinsky, J. Imgenberg, B. Kurz „Response of mature meniscal tissue tot a single injurious compression and interleukin-1 in vitro“ Osteoarthritis and Cartillage
>>Response of mature meniscal tissue to a single injurious compression and interleukin-1 in vitro
